Stat4 antibody
WebHowever, STAT4 phosphorylation results must be interpreted with caution due to the lack of a proper STAT4 antibody to assess total STAT4 expression by flow cytometry. For this reason, STAT4 is meant to help only in the diagnosis of other forms of MSMD. ... STAT4 encodes the signal transducer and activator of transcription 4 protein (STAT4), ... WebSystemic scleroderma. A normal variation in the STAT4 gene has been associated with an increased risk of developing systemic scleroderma, which is an autoimmune disorder characterized by the buildup of scar tissue (fibrosis) in the skin and internal organs. …
Stat4 antibody
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WebSTAT4 antibody Catalog Number: orb106501 Be the first to review this product Datasheet Select Product Size 100 μl 50 μl 200 μl Quantity Usually dispatched within 5-10 working days. In stock $0.00 Add to Cart Skip to the end of the images gallery Product Properties Reviews Write Your Own Review You're reviewing:STAT4 antibody - orb106501 Your Rating WebSTAT4 Antibodies Our range of STAT4 antibodies, which is one of the seven mammalian STAT family members, come in Antibody Only and Purified formats. These antibodies can be used for applications including western blotting and immunohistochemistry .
WebMar 21, 2024 · STAT4 (Signal Transducer And Activator Of Transcription 4) is a Protein Coding gene. Diseases associated with STAT4 include Systemic Lupus Erythematosus 11 and Systemic Lupus Erythematosus . Among its related pathways are Interleukin-12 … Webcytokine on STAT4 activation by the other and the downstream such as cytokine induction. We observe the effect of prior exposure to IL-12 or IFN- on the ability of T cells to subse-quently respond to the other cytokine. MATERIALS AND METHODS The Nottingham Research Ethics Committee (UK) approved this study. Cytokines and antibodies
WebAntibodies that detect STAT4 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, Flow Cytometry and ELISA. These antibodies target STAT4 in Human, Mouse and Rat samples. Our STAT4 … WebImmunogen. Synthetic peptide corresponding to human STAT4 phosphorylated at tyrosine 693. Formulation. Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA) Preparation. The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions.
WebDescription: This 4LURPIE monoclonal antibody recognizes human and mouse signal transducer and activator of transcription 4 (STAT4) when phosphorylated on tyrosine 693 (Y693). STAT proteins are activated by ligand binding to cytokine receptors that associate with Janus kinase (JAK) family members. great discovery gallery wikiWebSTAT4 Recombinant Rabbit Monoclonal Antibody (2H9L5) Advanced Verification This Antibody was verified by Cell treatment to ensure that the antibody binds to the antigen stated. View all (60) STAT4 antibodies Add To Cart Datasheet Protocols Questions & Answers Tech Support Antibody Testing Data (8) Advanced Verification (1) Application … great discovery transcriptWebOur STAT4 Antibodies can be used in a variety of model species: Human, Mouse, Rat. Use the list below to choose the STAT4 Antibody which is most appropriate for your research; you can click on each one to view full technical details, images, references, reviews and … great discovery nedirWebSTAT4 encodes the signal transducer and activator of transcription 4 protein (STAT4), ... Among anti-CCP positive NARAC patients (81 percent positive for anti-cyclic citrullinated peptide antibody), the rs7574865 minor allele frequency did not differ significantly (P > 0.05) in the subgroup that was positive for the antibody (0.28) and the ... great discovery uninstallWebMethods. We temporally assessed STAT4-dependent Tfh cell signaling with cytokine production and autoreactive B cell maturation during the course of murine lupus, with further assessment of Tfh cell gene transcription using RNA-seq. STAT4-dependent signaling and cytokine production were also determined in circulating Tfh-like cells in patients with SLE, … great discoveries in archaeologyWebThe leucocytes were washed, permeabilized with BD Phosflow™ Perm Buffer III (Cat. No. 558050) on ice for 30 minutes, washed, and then stained with BD Phosflow™R718 Mouse Anti-Stat4 (pY693) antibody (Cat. No.567631). The fluorescence histograms showing Stat4 (pY693) expression were derived from events with the forward and side light-scatter ... great discovery thomasWebHuman STAT4 is 748 amino acids (aa) in length. STAT4 mediates cytokine signaling by acting as a signal transducer in the cytoplasm and, upon phosphorylation, homo- or heterodimerizes with other STAT proteins, which then translocate to the nucleus and … great discovery virus