WebCinacalcet is a drug that acts as a calcimimetic (i.e. it mimics the action of calcium on tissues). Secondary hyperparathyroidism (HPT) in patients with chronic kidney disease … WebCinacalcet is a drug that acts as a calcimimetic [4] [6] (i.e. it mimics the action of calcium on tissues) by allosteric activation of the calcium-sensing receptor that is expressed in various human organ tissues. The calcium-sensing receptors on the surface of the chief cell of the parathyroid gland is the principal negative regulator of ...
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WebJul 11, 2024 · Cinacalcet is used to treat hyperparathyroidism (overactive functioning of the parathyroid glands) in people who are on long-term dialysis for kidney disease. Cinacalcet is also used to treat hypercalcemia (high levels of calcium in the blood) in people with … Commonly reported side effects of cinacalcet include: decreased plasma … Cinacalcet Interactions. There are 136 drugs known to interact with cinacalcet, … Cinacalcet is a member of the calcimimetics drug class and is commonly used for … WebAbstract. Oral cinacalcet hydrochloride (HCl) [Sensipar, Mimpara] is the first in a new class of therapeutic agents, the calcimimetics, and has a novel mechanism of action. It directly modulates the principal regulator of parathyroid hormone (PTH) secretion, namely the calcium-sensing receptor (CaR) on the chief cells in the parathyroid gland. early bronco coilover kit
Cinacalcet - Wikipedia
WebSep 12, 2024 · Cinacalcet Mylan is a medicine used in adults and older patients to: treat secondary hyperparathyroidism in patients with serious kidney disease who need dialysis … WebCinacalcet is a drug that acts as a calcimimetic [4] [6] (i.e. it mimics the action of calcium on tissues) by allosteric activation of the calcium-sensing receptor that is expressed in … WebUses. Cinacalcet is used to treat increased amounts of a certain hormone (parathyroid) in people with long-term kidney disease who are on … csswebpd2/cssolution