Atf6 kda
WebAll lanes : Anti-ATF6 antibody (ab83504) at 1 µg/ml Lane 1 : Wild-type HeLa cell lysate Lane 2 : ATF6 knockout HeLa cell lysate Lysates/proteins at 20 µg per lane. Performed under … WebMetabolic changes are an important component of tumor cell progression. Tumor cells adapt to environmental stresses via changes to carbohydrate and lipid metabolism. Autophagy, a physiological process in mammalian cells that digests damaged organelles and misfolded proteins via lysosomal degradation, is closely associated with metabolism in mammalian …
Atf6 kda
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WebATF6. ATF6 is a 90-kDa protein that translocates from the ER to the Golgi in response to stress, ... that travels to the nucleus and alters gene expression. ATF6 processing can … Web(4, 5). When ATF6 traveled to Golgi during ER stress, the high mannose N-glycan of ATF6 was trimmed by glycosidases in the Golgi to produce an Endo H-resistant full-length …
WebFilm was exposed for 1 min. The top arrow corresponds to the 90 kDa form of ATF6 described as full-length in the literature. The human full-length and partial length ATF6 plasmids are described in Luo and Lee (2002). Image from the standard format of this antibody. quantity: 0.1 mg price: 429 USD to the supplier WebJan 4, 2024 · HCPT activated ERS-mediated apoptosis through the ATF6 pathway. Expressions of ERS- and apoptosis-related proteins after administrations with different …
WebATF6 is a key transcriptional activator of the unfolded protein response (UPR), which allows mammalian cells to maintain cellular homeostasis when they are subjected to a variety of … Web2 5 KD a - 3 7 KD a - Scra mb le mi R -7 6 8 -3 p Anmi mi cs 1 0 0 KD a - -A T F 6 Scra mb le ti-mi R -7 6 8 -3 p + - - + H EMn -MP -G APD H 2 5 KD a - 3 7 KD a - -Bcl -2 1 0 0 KD a - -A T F 6 A B Supplementary Figure 4: The endogenous levels of Bcl-2 and ATF6 that are
Webfull-length and cleaved forms ATF6 were detected with IMG-273. The results show that in addition to the major 90 kDa full length ATF6, protein bands over the range of 50-70 kDa …
WebApr 5, 2024 · In the beginning, BSJ-04-132 is a selective Ribociclib-based CDK4 degrader ( PROTAC ), with IC 50 s of 50.6 nM and 30 nM for CDK4/D1 and CDK6/D1, respectively. Meanwhile, BSJ-04-132 does not induce CDK6 and IKZF1/3 degradation. Particularly, BSJ-04-132 has anti-cancer activity. In the second place, BSJ-04-132 only results in the … hydroxy lean caloriesWebApr 12, 2024 · 2004 Differential contributions of ATF6 and XBP1 to the activation of endoplasmic reticulum stress-responsive cis-acting elements ERSE, UPRE and ERSE-II. J. ... Okajima T, Xu A, Lei L, Irvine KD. 2005 Chaperone activity of protein O-fucosyltransferase 1 promotes notch receptor folding. Science 307, 1599-1603. hydroxy lean chemist warehouseWebFeb 18, 2024 · Importantly, the effects of ATF6 deletion on TGFβ-mediated induction of fibroblast marker genes were recapitulated by siRNA-mediated knockdown (KD) of ATF6 in WT AMVFs (Figure 2 D–F). In contrast, when ATF6 was activated by treating WT AMVFs with 10 μM compound 147, a small-molecule activator of ATF6 [ 28 , 29 , 30 ], for 48 h, … hydroxyl chemical propertiesWebER stress-related ATF6 upregulates CIP2A and contributes to poor prognosis of colon cancer. Chun Yu Liu, Chia Chi Hsu, Tzu Ting Huang, Chia Han Lee, Ji Lin Chen, Shung Haur Yang, Jeng Kai Jiang, Wei Shone Chen, Kuan Der Lee, Hao Wei Teng. mass of ozoneWebMar 19, 2004 · ATF6 is a key transcriptional activator of the unfolded protein response (UPR), which allows mammalian cells to maintain cellular homeostasis when they are … mass of oxygen in waterWebFeb 3, 2024 · western blot结果表明，与对照组相比，lps显著升高perk(p0.05)、atf6(p0.01)、grp78(p0.01)和chop(p0.01)的蛋白表达(图1c～h)。免疫荧光结果进一步证实，与对照组相比，lps可升高grp78的荧光强度(图1i)。因此，lps可诱导奶牛乳腺上皮细胞发生内质网应激，并激活perk和atf6信号通路。 hydroxyl chemical compoundWebAll lanes : Anti-ATF6 antibody (ab37149) at 1 µg/ml Lane 1 : Mouse Heart Lysate Lane 2 : Mouse Skeletal Muscle Lysate Lysates/proteins at 15 µg per lane. Secondary All lanes : … hydroxyl chemical formula